Although she started out being a member of a church choir at Order Christian Church, Mfene was destined for more. After honing her singing skills with the choir, another opportunity availed itself, and soon Mfene was not only a member of the successful choir Lord Comforters, but also their lead singer. She stayed with the group for an incredible 16 years until the urge to go solo became too strong, and she gave into it.
Her album, Akamlahli Onowakhe, which she released after going solo was met with highly positive responses.
